🌟Actors Isaiah Washington and T.R. Knight left amid controversy and backstage tension.
🎭Kate Walsh left to star in the Grey's Anatomy spin-off, Private Practice.
💔T.R. Knight's character, George O'Malley, was written off the show due to lack of screen time.
🏆Katherine Heigl's departure followed public criticism of the show and her decision to withdraw from Emmy consideration.
💔Sandra Oh wanted to explore new creative opportunities and emotionally let go of her character.