Colin predicts the Bills to win against the Jaguars, citing their superior form and Jacksonville's recent struggles.
Colin believes the Saints will defeat the Patriots, highlighting potential weaknesses in New England's offense and the return of key players for New Orleans.
Colin expects the Colts to pull off an upset against the Titans, emphasizing their strong performance against the Rams and the emotional momentum they carry.
Colin predicts Kirk Cousins will outperform Patrick Mahomes in passing yards, citing Mahomes' struggles and Cousins' potential for a breakout game.