🔍Autoimmune diseases occur when the immune system attacks the body's cells or tissues.
🩺Pemphigus vulgaris (PV) is an autoimmune disease that affects the skin, causing blisters and inflammation.
💉The immune therapy involves using engineered killer T-cells to target and eliminate disease-causing B-cells.
🔬Lab tests and experiments on mice have shown promising results for the effectiveness and safety of the therapy.
🌍The therapy holds potential for treating other autoimmune diseases beyond PV.
What are autoimmune diseases?
—Autoimmune diseases occur when the immune system mistakenly attacks and damages the body's own healthy cells or tissues.
What is pemphigus vulgaris?
—Pemphigus vulgaris (PV) is an autoimmune disease that primarily affects the skin, causing blisters and sores.
How does the immune therapy work?
—The immune therapy involves engineering killer T-cells to recognize and eliminate disease-causing B-cells, potentially curing autoimmune diseases like PV.
What are the results of the therapy in lab tests and mice?
—Lab tests and experiments on mice have shown promising results, with the engineered killer T-cells effectively targeting and eliminating disease-causing B-cells without harming healthy cells.
Can this therapy be used for other autoimmune diseases?
—Yes, the therapy holds potential for treating other autoimmune diseases beyond pemphigus vulgaris.
00:00Researchers from the University of Pennsylvania have developed a breakthrough immune therapy to cure autoimmune diseases.
01:32Pemphigus vulgaris (PV) is a specific autoimmune disease that affects the skin, causing inflammation and blisters.
03:23The immune therapy involves engineering killer T-cells to recognize and eliminate disease-causing B-cells, potentially curing PV.
03:55Lab tests and experiments on mice have shown promising results for the therapy's effectiveness and safety.
04:41The therapy holds potential for treating other autoimmune diseases besides PV.
