The Role of Vitamin K2 in Chronic Kidney Disease

TLDRVitamin K2 plays a crucial role in preventing calcification of blood vessels in chronic kidney disease patients. Supplementing with vitamin K2 can reduce the risk of cardiovascular disease and mortality in these patients.

Key insights

🩺Chronic kidney disease patients have a higher risk of dying from cardiovascular disease than progressing to dialysis.

🔑Calcification of blood vessels occurs as kidney function declines and the body has a harder time getting rid of phosphorus.

🌿Vitamin K2, found in fermented foods and poultry, is important in preventing calcification and reducing fracture risk.

💊Vitamin K2 absorption is affected by gut dysbiosis, phosphate binders, antibiotics, and proton pump inhibitors.

⚕️MK7, a type of vitamin K2, shows promise in reducing calcification, but longer studies are needed.

Q&A

What is the role of vitamin K2 in chronic kidney disease?

Vitamin K2 helps prevent calcification of blood vessels in chronic kidney disease by activating the matrix gla protein.

What are the food sources of vitamin K2?

Fermented foods, natto, cheese, butter, egg yolks, poultry, and liver are rich in vitamin K2.

Can vitamin K2 supplements increase the risk of blood clots?

No, vitamin K2 supplements do not increase the risk of blood clots, even at high doses.

Who should not supplement with vitamin K2?

Patients taking vitamin K antagonists like coumadin or warfarin should avoid supplementing with vitamin K2.

What is the recommended type of vitamin K2 to take?

MK7 is the preferred type of vitamin K2, as it has better absorption and a longer half-life.

Timestamped Summary

00:00Patients with chronic kidney disease are more likely to die from cardiovascular disease than progress to dialysis.

03:18Calcification occurs in the blood vessels as kidney function declines and the body struggles to eliminate phosphorus.

06:04Vitamin K2, found in fermented foods, poultry, and liver, plays a crucial role in preventing calcification and reducing fracture risk.

07:56Gut dysbiosis, phosphate binders, antibiotics, and proton pump inhibitors can decrease vitamin K2 absorption.

08:11MK7, a type of vitamin K2, shows potential in reducing calcification, but longer studies are needed for conclusive results.