Speedrunning Plague Inc: Beating Every Plague on Mega Brutal

💡As soon as a popup appears, press 3 to increase the speed of the game and take advantage of this time to make important decisions.

🌍Focus on infectivity at the beginning by selecting symptoms that increase the spread of the plague. Then, prioritize air and water transmissions to reach difficult-to-infect countries.

🔬Choose genetic codes that decrease mutation chance, increase chances of spreading by sea, and provide minor bonuses in various environments.

💀Wait until there are no healthy people left in the world before focusing on lethality. Killing people too quickly can lead to closed borders and failed runs.

⏱️Timing is crucial for Spore bursts and eruptions. Use them strategically to infect new countries and ensure the spread of the plague.

What starting location is recommended for speedrunning Plague Inc?

—Starting in Saudi Arabia is recommended, as it is close to Europe, Asia, and Africa, and has both an airport and sea port.

Which genetic code should I use for a successful speedrun?

—Recommended genetic codes include ATP Boost, Genetic Mimic, Suppression, Herbal File, and Path Stasis.

When should I start focusing on lethality?

—Wait until there are no healthy people left in the world before increasing lethality to avoid closed borders.

How can I ensure the spread of the plague to difficult-to-infect countries?

—Focus on air and water transmissions, and choose symptoms and genetic codes that enhance infectivity in these regions.

What is the key to a successful Spore burst strategy?

—Use Spore bursts strategically, targeting countries with high population density and development, to maximize spread and increase DNA points.

00:08Increase game speed by pressing 3 as soon as a popup appears.

00:17Select genetic codes that decrease mutation chance and increase chances of spreading by sea.

00:32Focus on infectivity at the beginning, then prioritize air and water transmissions.

01:41Wait until there are no healthy people left in the world before focusing on lethality.

08:49Use Spore bursts strategically to infect new countries.