Fatty Acid Biosynthesis: Unlocking the Secrets of Fat Formation

🔬Fatty acid biosynthesis occurs in the cytosol and requires acetyl CoA, ATP, and NADPH.

⚙️The condensation reaction between acetyl CoA and malonyl CoA, catalyzed by fatty acid synthase, leads to the formation of a 4-carbon molecule.

💡Reduction reactions convert 3-hydroxyacyl-ACP and trans-2-enoyl-ACP to 3-oxoacyl-ACP and butyryl-ACP, respectively.

🌬️Dehydration and reduction reactions result in the formation of butyryl-ACP and finally, palmitic acid.

🧪Fatty acid biosynthesis involves multiple cycles, including cycle 2 and cycle 7, to elongate the fatty acid chain.

Where does fatty acid biosynthesis occur?

—Fatty acid biosynthesis takes place in the cytosol.

What are the key reactants required for fatty acid synthesis?

—Fatty acid biosynthesis requires acetyl CoA, ATP, and NADPH.

What is the final product of fatty acid biosynthesis?

—The final product is palmitic acid, a 16-carbon saturated fatty acid.

Which enzyme catalyzes the condensation reaction in fatty acid biosynthesis?

—The condensation reaction is catalyzed by fatty acid synthase.

What are the cycles involved in fatty acid elongation?

—Fatty acid elongation involves cycle 2 and cycle 7.

00:00In this video, we explore the process of fatty acid biosynthesis in the cytosol.

00:50Fatty acid biosynthesis requires acetyl CoA, ATP, and NADPH as key reactants.

03:13The condensation reaction between acetyl CoA and malonyl CoA, catalyzed by fatty acid synthase, leads to the formation of a 4-carbon molecule.

04:35Reduction reactions convert 3-hydroxyacyl-ACP and trans-2-enoyl-ACP to 3-oxoacyl-ACP and butyryl-ACP, respectively.

05:50Dehydration and reduction reactions result in the formation of butyryl-ACP and finally, palmitic acid.

08:25Fatty acid biosynthesis involves multiple cycles, including cycle 2 and cycle 7, to elongate the fatty acid chain.

10:10Fatty acid biosynthesis is a complex process that allows the production of palmitic acid, a vital component of lipid metabolism.