💡Enzymes are vital for digestion and breaking down biomolecules in the human body.
🔬Cofactors and coenzymes assist enzymes in their catalytic function.
🚫Inhibitors can block enzyme activity, either competitively or noncompetitively.
🔄Feedback inhibition is a regulatory mechanism that controls enzyme activity.
💊Medications often target enzymes to treat diseases and disorders.
What are some examples of enzymes in the human body?
—Amylase, lipase, pepsin, trypsin, and nucleases are enzymes that break down carbohydrates, lipids, proteins, and nucleic acids, respectively.
What are cofactors and coenzymes?
—Cofactors are inorganic substances like zinc or iron, while coenzymes are organic substances like vitamins. They assist enzymes in their catalytic function.
How do inhibitors affect enzyme activity?
—Inhibitors can block enzyme activity. Competitive inhibitors bind to the active site, while noncompetitive inhibitors bind elsewhere, causing a conformational change in the enzyme.
What is feedback inhibition?
—Feedback inhibition is a regulatory mechanism where the final product of a metabolic pathway acts as a noncompetitive inhibitor, blocking an earlier enzyme in the pathway to prevent excessive product formation.
Why is it important to understand enzymes in medication development?
—Enzymes are often targeted by medications to treat diseases and disorders. Understanding enzymes helps in developing effective medications that can regulate enzyme activity.
01:04Enzyme examples are important for understanding their significance in living things, particularly in digestion.
03:22Cofactors and coenzymes assist enzymes in their catalytic function, with cofactors being inorganic and coenzymes being organic.
04:36Inhibitors can block enzyme activity, either competitively or noncompetitively, affecting their ability to bind with substrates.
05:45Feedback inhibition is a regulatory mechanism where the final product of a metabolic pathway acts as a noncompetitive inhibitor to prevent excessive product formation.
06:55Enzymes are often targeted by medications to treat diseases and disorders, such as ACE inhibitors for high blood pressure.
