Addressing the audience directly in Sex and the City's first season was quickly abandoned due to viewer backlash.
Two and a Half Men's final episode featured a meta fourth wall break, which did not sit well with fans.
The office's reveal of the camera crew broke the illusion of the documentary-style format.
Ed Sheeran's cameo in Game of Thrones was criticized as a distracting and immersion-breaking moment.
Saved by the Bell's protagonist, Zach Morris, frequently froze time by calling a 'timeout', which felt out of place in an otherwise grounded show.